Low Base-Substitution Mutation Rate but High Rate of Slippage Mutations in the Sequence Repeat-Rich Genome of Dictyostelium discoideum

We describe the rate and spectrum of spontaneous mutations for the social amoeba Dictyostelium discoideum, a key model organism in molecular, cellular, evolutionary and developmental biology. Whole-genome sequencing of 37 mutation accumulation lines of D. discoideum after an average of 1,500 cell di...

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Bibliografische gegevens

Hoofdauteurs:	Sibel Kucukyildirim, Megan Behringer, Way Sung, Debra A. Brock, Thomas G. Doak, Hatice Mergen, David C. Queller, Joan E. Strassmann, Michael Lynch
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Oxford University Press 2020-09-01
Reeks:	G3: Genes, Genomes, Genetics
Onderwerpen:	dictyostelium discoideum drift-barrier hypothesis insertion-deletion bias mutation simple sequence repeats
Online toegang:	http://g3journal.org/lookup/doi/10.1534/g3.120.401578
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