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Effects of canagliflozin on growth and metabolic reprograming in hepatocellular carcinoma cells: Multi-omics analysis of metabolomics and absolute quantification proteomics (iMPAQT).

AIM:Metabolic reprograming is crucial in the proliferation of hepatocellular carcinoma (HCC). Canagliflozin (CANA), a sodium-glucose cotransporter 2 (SGLT2) inhibitor, affects various metabolisms. We investigated the effects of CANA on proliferation and metabolic reprograming of HCC cell lines using...

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Bibliografiske detaljer
Principais autores: Dan Nakano, Takumi Kawaguchi, Hideki Iwamoto, Masako Hayakawa, Hironori Koga, Takuji Torimura
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2020-01-01
Serier:PLoS ONE
Online adgang:https://doi.org/10.1371/journal.pone.0232283
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