Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance

Summary: Elucidating the mechanisms of resistance to immunotherapy and developing strategies to improve its efficacy are challenging goals. Bioinformatics analysis demonstrates that high CDK6 expression in melanoma is associated with poor progression-free survival of patients receiving single-agent...

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Autori principali:	Xueliang Gao, Yongxia Wu, Joel M. Chick, Andrea Abbott, Baishan Jiang, David J. Wang, Susana Comte-Walters, Roger H. Johnson, Nathaniel Oberholtzer, Michael I. Nishimura, Steven P. Gygi, Anand Mehta, Denis C. Guttridge, Lauren Ball, Shikhar Mehrotra, Piotr Sicinski, Xue-Zhong Yu, Haizhen Wang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2023-04-01
Serie:	Cell Reports
Soggetti:	CP: Cancer CP: Immunology
Accesso online:	http://www.sciencedirect.com/science/article/pii/S221112472300325X
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