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Diagnostic and prognostic utility of a DNA hypermethylated gene signature in prostate cancer.

We aimed to identify a prostate cancer DNA hypermethylation microarray signature (denoted as PHYMA) that differentiates prostate cancer from benign prostate hyperplasia (BPH), high from low-grade and lethal from non-lethal cancers. This is a non-randomized retrospective study in 111 local Asian men...

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Principais autores: Liang Kee Goh, Natalia Liem, Aadhitthya Vijayaraghavan, Gengbo Chen, Pei Li Lim, Kae-Jack Tay, Michelle Chang, John Soon Wah Low, Adita Joshi, Hong Hong Huang, Emarene Kalaw, Puay Hoon Tan, Wen-Son Hsieh, Wei Peng Yong, Joshi Alumkal, Hong Gee Sim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3953552?pdf=render
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