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Does Vancomycin as the First-Choice Therapy for Antibiotic Prophylaxis Increase the Risk of Surgical Site Infections Following Spine Surgery?

Surgical site infections (SSIs) remain a significant complication in spine surgery, especially in instrumented procedures with long operative times. Although guidelines recommend cefazolin as the first-line agent due to its efficacy against Staphylococcus aureus, predictable pharmacokinetics, and sa...

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Principais autores: Vojislav Bogosavljevic, Dusan Spasic, Lidija Stanic, Marija Kukuric, Milica Bajcetic
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-10-01
Serier:Antibiotics
Fag:
surgical site infections (SSIs)
spinal surgery
antibiotic prophylaxis
vancomycin
cefazolin
antimicrobial resistance (AMR)
Online adgang:https://www.mdpi.com/2079-6382/14/10/996
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