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A method for constructing interpretable hidden Markov models for the task of identifying binding cores in sequences

Solving the problem of predicting the immune response against foreign protein sequence fragments processed by cells is one of the major milestones on the road to the personalized cancer vaccine development. The selection of peptides participating in the immune response is a complex multi-stage proce...

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Autori principali: D. A. Kleverov, A. A. Shalyto, M. N. Artyomov
Natura: Artigo
Lingua:Inglês
Pubblicazione: ITMO University 2024-12-01
Serie:Научно-технический вестник информационных технологий, механики и оптики
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Accesso online:https://ntv.elpub.ru/jour/article/view/187
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