Alternate pathways of bile acid synthesis in the cholesterol 7α-hydroxylase knockout mouse are not upregulated by either cholesterol or cholestyramine feeding

Bile acids are synthesized via the classic pathway initiated by cholesterol 7α-hydroxylase (CYP7A1), and via alternate pathways, one of which is initiated by sterol 27-hydroxylase (CYP27). These studies used mice lacking cholesterol 7α-hydroxylase (Cyp7a1−/−) to establish whether the loss of the cla...

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Bibliografische gegevens

Hoofdauteurs:	Margrit Schwarz, David W. Russell, John M. Dietschy, Stephen D. Turley
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2001-10-01
Reeks:	Journal of Lipid Research
Onderwerpen:	bile acid pool size biliary bile acid biliary cholesterol cholesterol absorption cholesterol synthesis fecal sterol excretion
Online toegang:	http://www.sciencedirect.com/science/article/pii/S0022227520322136
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