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Inhibitory action of gemfibrozil on cholesterol absorption in rat intestine

This study was designed to determine whether gemfibrozil inhibits intestinal lipid absorption. Male Sprague-Dawley rats received an oral dose of 30 mg gemfibrozil/kg body weight for 14 days. Mesenteric lymph cannulation was performed, and a lipid infusion containing 40 μmol/h (35.4 mg/h) of radiolab...

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Bibliographic Details
Main Authors: Yoh Umeda, Yuko Kako, Kayo Mizutani, Yohji Iikura, Mitsunobu Kawamura, Mitsuru Seishima, Hiroshi Hayashi
Format: Artigo
Language:Inglês
Published: Elsevier 2001-08-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520315716
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