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Sirolimus in Infants with Multiple Cardiac Rhabdomyomas Associated with Tuberous Sclerosis Complex

Introduction: Cardiac rhabdomyomas represent a frequent manifestation of tuberous sclerosis. Tumor growth, mainly prenatally, can result in intrauterine fetal or neonatal deaths in almost 10% of patients. Case Report: We treated 3 consecutive infants aged less than 12 months with sirolimus, an oral...

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Principais autores: Maurizio Lucchesi, Enrico Chiappa, Flavio Giordano, Francesco Mari, Lorenzo Genitori, Iacopo Sardi
Format: Artigo
Sprog:Inglês
Udgivet: Karger Publishers 2018-06-01
Serier:Case Reports in Oncology
Fag:
mTOR inhibitors
Sirolimus
Tuberous sclerosis complex
Cardiac rhabdomyomas
Subpendymal giant cell astrocytomas
Online adgang:https://www.karger.com/Article/FullText/490662
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