Upregulation of TGF-β-induced HSP27 by HSP90 inhibitors in osteoblasts

Abstract Background Heat shock protein (HSP) 90 functions as a molecular chaperone and is constitutively expressed and induced in response to stress in many cell types. We have previously demonstrated that transforming growth factor-β (TGF-β), the most abundant cytokine in bone cells, induces the ex...

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Manylion Llyfryddiaeth

Prif Awduron:	Gen Kuroyanagi, Haruhiko Tokuda, Kazuhiko Fujita, Tetsu Kawabata, Go Sakai, Woo Kim, Tomoyuki Hioki, Junko Tachi, Rie Matsushima-Nishiwaki, Takanobu Otsuka, Hiroki Iida, Osamu Kozawa
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	BMC 2022-05-01
Cyfres:	BMC Musculoskeletal Disorders
Pynciau:	Heat shock protein HSP90 HSP90 inhibitor HSP27 TGF-β SAPK/JNK
Mynediad Ar-lein:	https://doi.org/10.1186/s12891-022-05419-1
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!