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The causal relationship between body mass index and perianal abscess: a Mendelian randomization study

Abstract Background Observational studies suggest an association between elevated body mass index (BMI) and perianal abscess risk, but residual confounding and reverse causality limit causal inference. Mendelian randomization (MR) offers a robust approach to assess causality by leveraging genetic va...

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Principais autores: Long Wu, Huan Wu, Xiao-Yun Li, Yun-Huan Zhen, Hai-Yang Li
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-12-01
Serier:BMC Gastroenterology
Fag:
BMI
Perianal abscess
Mendelian randomization
Single nucleotide polymorphisms
Causal association
Online adgang:https://doi.org/10.1186/s12876-025-04555-x
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