Infected erythrocyte choline carrier inhibitors: exploring some potentialities inside Plasmodium phospholipid metabolism for eventual resistance acquisition

We have developed a model for designing antimalarial drugs based on interference with an essential metabolism developed by Plasmodium during its intraerythrocytic cycle, phospholipid (PL) metabolism. The most promising drug interference is choline transporter blockage, which provides Plasmodium with...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Henri J. Vial, Marie L. Ancelin, Noureddine Elabbadi, Hélène Orcel, Hye-Jeong Yeo, Catherine Gumila
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Fundação Oswaldo Cruz (FIOCRUZ) 1994-01-01
سلاسل:	Memorias do Instituto Oswaldo Cruz
الموضوعات:	malaria phospholipid metabolism choline carrier serine lipidic metabolism resistance
الوصول للمادة أونلاين:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761994000600021
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!