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PEGylated therapeutics in the clinic

Abstract The covalent attachment of polyethylene glycol (PEG) to therapeutic agents, termed PEGylation, is a well‐established and clinically proven drug delivery approach to improve the pharmacokinetics and pharmacodynamics of drugs. Specifically, PEGylation can improve the parent drug's solubility,...

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Principais autores: Yongsheng Gao, Maithili Joshi, Zongmin Zhao, Samir Mitragotri
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2024-01-01
Series:Bioengineering & Translational Medicine
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Acceso en liña:https://doi.org/10.1002/btm2.10600
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