Maternal dendritic cells influence fetal allograft response following murine in-utero hematopoietic stem cell transplantation

Abstract Background Intrauterine hematopoietic stem cell transplantation (IUT), potentially curative in congenital haematological disease, is often inhibited by deleterious immune responses to donor cells resulting in subtherapeutic donor cell chimerism (DCC). Microchimerism of maternal immune cells...

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Autors principals:	Karthikeyan Kandasamy, Nuryanti Binti Johana, Lay Geok Tan, Yvonne Tan, Julie Su Li Yeo, Nur Nazneen Binte Yusof, Zhihui Li, Jiayu Koh, Florent Ginhoux, Jerry K. Y. Chan, Mahesh Choolani, Citra N. Z. Mattar
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2023-05-01
Col·lecció:	Stem Cell Research & Therapy
Matèries:	Hematopoietic stem cells In-utero transplantation Fetal tolerance Maternal microchimerism
Accés en línia:	https://doi.org/10.1186/s13287-023-03366-9
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