The effects of sulfated secondary bile acids on intestinal barrier function and immune response in an inflammatory in vitro human intestinal model

Dysbiosis-related perturbations in bile acid (BA) metabolism were observed in inflammatory bowel disease (IBD) patients, which was characterized by increased levels of sulfated BAs at the expense of secondary BAs. However, the exact effects of sulfated BAs on the etiology of IBD are not investigated...

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Bibliografiske detaljer

Principais autores:	Benthe van der Lugt, Maartje C.P. Vos, Mechteld Grootte Bromhaar, Noortje Ijssennagger, Frank Vrieling, Jocelijn Meijerink, Wilma T. Steegenga
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2022-02-01
Serier:	Heliyon
Fag:	Inflammatory bowel disease Secondary bile acids Sulfation Intestinal barrier function Mucus layer
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2405844022001712
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