Re-evaluating Treatments for Advanced Urothelial Carcinoma Using Restricted Mean Survival Time: A Systematic Review and Network Meta-analysis

Background and objective: The proportional hazards (PH) assumption may not hold for immune checkpoint inhibitor (ICI) trials because of delayed treatment effects. We assessed PH validity in trials of first-line treatment in advanced urothelial carcinoma (UC) and compared treatments using restricted...

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Hlavní autoři:	Shugo Yajima, Wei Chen, Kohei Hirose, Akihiro Hirakawa, Kenji Tanabe, Motohiro Fujiwara, Hiroshi Fukushima, Hajime Tanaka, Hitoshi Masuda, Yasuhisa Fujii, Soichiro Yoshida
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2026-03-01
Edice:	European Urology Open Science
Témata:	Immune checkpoint inhibitors Network meta-analysis Proportional hazards Restricted mean survival time Urothelial carcinoma
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2666168326000200
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