Macrophage polarization in rheumatoid arthritis: signaling pathways, metabolic reprogramming, and crosstalk with synovial fibroblasts

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation and progressive joint destruction. Macrophages are key effector cells that play a central role in RA pathogenesis through their ability to polarize into distinct functional phenotypes. An imba...

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Hlavní autoři:	Yixin Zheng, Kai Wei, Ping Jiang, Jianan Zhao, Yu Shan, Yiming Shi, Fuyu Zhao, Cen Chang, Yunshen Li, Mi Zhou, Xinliang Lv, Shicheng Guo, Dongyi He
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-05-01
Edice:	Frontiers in Immunology
Témata:	rheumatoid arthritis inflammation macrophages macrophage polarization fibroblasts
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1394108/full
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