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Ferrostatin-1 prevents transfusion-related acute lung injury in mice by inhibiting ferroptosis

[Objective] To investigate the role of ferroptosis in transfusion-related acute lung injury (TRALI) and evaluate the efficacy of the specific inhibitor Ferrostatin-1 (Fer-1), thereby to provide a basis for the prevention and treatment of TRALI. [Methods] This study utilized a ”2-hit” model to induce...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: LIU Siwei, XIAO Ling, XU Haixia, CHENG Jiale, TIAN Li, LIU Zhong
Format: Artigo
Sprache:Chinês
Veröffentlicht: Institute of Blood Transfusion of Chinese Academy of Medical Sciences 2025-08-01
Schriftenreihe:Zhongguo shuxue zazhi
Schlagworte:
ferroptosis
transfusion-related acute lung injury
ferrostatin-1
lipid peroxidation
2-hit model
Online-Zugang:https://www.cjbt.cn/thesisDetails#10.13303/j.cjbt.issn.1004-549x.2025.08.002&lang=en
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