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Influenza A virus infection impairs neuronal activity in human iPSC-derived NGN2 neural co-cultures

Abstract Influenza A virus (IAV) infection is associated with a wide variety of neurological complications, of which mild complications like impaired cognitive functioning are most prominent. Even though several studies have shown that many influenza viruses can enter the CNS, the neuropathogenesis...

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Asıl Yazarlar: Feline F. W. Benavides, Annabel L. V. Kempff, Hilde Smeenk, Bas Lendemeijer, Marla Lavrijsen, Johan A. Slotman, Steven A. Kushner, Femke M. S. de Vrij, Lisa Bauer, Debby van Riel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2026-04-01
Seri Bilgileri:Acta Neuropathologica Communications
Konular:
Influenza A viruses
hiPSC-derived neural co-culture
NGN2 neuron
Micro-electrode array system (MEA)
Neuronal activity
Cognitive impairment
Online Erişim:https://doi.org/10.1186/s40478-026-02292-0
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