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Notch signaling stabilizes lengths of motile cilia in multiciliated cells in the lung

By stabilizing the ciliary length and preserving the proximal-distal gradient, Notch signaling acts as a key regulator of multiciliated cell homeostasis, a process disrupted during Mycobacterium tuberculosis infection, likely through suppression of the Notch–PROM1 axis. Airway multiciliated cells (M...

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Furkejuvvon:
Váldodahkkit: Neenu Joy, Aditya Deshpande, Sai Manoz Lingamallu, Vasam Manjveekar Prabantu, Chakenalli N Naveenkumar, Kumaraswamy Bharathkumar, Sukanya Bhat, Zabdiel Alvarado-Martinez, Alessandra Livraghi-Butrico, James S Hagood, Richard C Boucher, Daniel Lafkas, Kevin M Byrd, Shridhar Narayanan, Radha K Shandil, Arjun Guha
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Life Science Alliance LLC 2026-03-01
Ráidu:Life Science Alliance
Liŋkkat:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202503268
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