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Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats

Malaria is a global health burden, with Plasmodium falciparum (Pf) and Plasmodium vivax (Pv) responsible for the majority of infections worldwide. Circumsporozoite protein (CSP) is the most abundant protein on the surface of Plasmodium sporozoites, and antibodies targeting the central repeat region...

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Principais autores: Iga Kucharska, Lamia Hossain, Danton Ivanochko, Qiren Yang, John L Rubinstein, Régis Pomès, Jean-Philippe Julien
格式: Artigo
语言:Inglês
出版: eLife Sciences Publications Ltd 2022-01-01
丛编:eLife
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在线阅读:https://elifesciences.org/articles/72908
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