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Multifunctional effect of flavonoids from Millettia brandisiana against Alzheimer's disease pathogenesis

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive impairment and neuronal death. Fifteen flavonoids from Millettia brandisiana were evaluated for the multifunctional effect against AD pathogenesis, including butyrylcholine esterase (BuChE) inhibition, anti-amyloid b...

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Principais autores: Puguh Novi Arsito, Pornthip Waiwut, Chavi Yenjai, Supakorn Arthan, Orawan Monthakantirat, Natsajee Nualkaew, Pitchayakarn Takomthong, Chantana Boonyarat
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2023-11-01
coleção:Heliyon
Assuntos:
Multi-mode of action
Butyrylcholine esterase
Amyloid beta
Neuroprotection
Molecular docking
Structure-activity relationship
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2405844023091028
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