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Targeted Protein Degradation: Principles and Applications of the Proteasome

The proteasome is a multi-catalytic protease complex that is involved in protein quality control via three proteolytic activities (i.e., caspase-, trypsin-, and chymotrypsin-like activities). Most cellular proteins are selectively degraded by the proteasome via ubiquitination. Moreover, the ubiquiti...

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Bibliografski detalji
Glavni autori: Yosup Kim, Eun-Kyung Kim, Yoona Chey, Min-Jeong Song, Ho Hee Jang
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2023-07-01
Serija:Cells
Teme:
Online pristup:https://www.mdpi.com/2073-4409/12/14/1846
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