Flow molecular dynamics simulations reveal mechano-presentation of von Willebrand factor through glycan-modulated autoinhibitory modules
Force-induced protein conformational changes govern many essential biological processes, yet their molecular mechanisms remain difficult to resolve. Von Willebrand factor (VWF), a central regulator of hemostasis, is activated by hydrodynamic forces in blood flow, but how mechanical signals propagate...
I tiakina i:
| Ngā kaituhi matua: | , , |
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| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
AIP Publishing LLC
2026-05-01
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| Rangatū: | APL Bioengineering |
| Urunga tuihono: | https://pubs.aip.org/aip/apb/article-pdf/doi/10.1063/5.0329754/21004378/026105_1_5.0329754.pdf |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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