Biological and genetic characterization of a newly established human primary multidrug-resistant distal cholangiocarcinoma cell line, CBC3T-6

Abstract Distal cholangiocarcinoma is a rare and highly aggressive malignant tumor. The inherent tumor characteristics and growth pattern of cancer cells pose a challenge for diagnosis and treatment. Chemotherapy resistance leads to limited treatment options for patients with advanced cholangiocarci...

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Autores principales:	Mingzhen Bai, Ruoshui Wang, Chongfei Huang, Ruyang Zhong, Ningzu Jiang, Wenkang Fu, Ningning Mi, Long Gao, Yuyao Jin, Haidong Ma, Jie Cao, Haiying Yu, Qiang Jing, Chao Zhang, Ping Yue, Yong Zhang, Yanyan Lin, Hengwei Zhang, Wenbo Meng
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2024-11-01
Colección:	Scientific Reports
Materias:	Distal cholangiocarcinoma Cell line Multidrug resistance KRAS mutations TP53 mutations
Acceso en línea:	https://doi.org/10.1038/s41598-024-81392-0
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