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Prognostic value of prelymphodepletion absolute lymphocyte counts in relapsed/refractory diffuse large B-cell lymphoma patients treated with chimeric antigen receptor T cells

IntroductionChimeric antigen receptor (CAR) T cell therapy has achieved unprecedented efficacy recently. However, the factors related to responses and durable remission are elusive. This study was to investigate the impact of pre-lymphodepletion (pre-LD) absolute lymphocyte count (ALC) on CAR T cell...

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Principais autores: Yanyan Lu, Hong Zhu, Yang Liu, Ying Wang, Yinxiang Sun, Hai Cheng, Zhiling Yan, Jiang Cao, Wei Sang, Feng Zhu, Depeng Li, Haiying Sun, Junnian Zheng, Kailin Xu, Zhenyu Li
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-05-01
coleção:Frontiers in Immunology
Assuntos:
chimeric antigen receptor T cell
diffuse large B-cell lymphoma
prelymphodepletion absolute
prognostic value
survival time
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1155216/full
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