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Crystal structures of the NO sensor NsrR reveal how its iron-sulfur cluster modulates DNA binding

NsrR is a bacterial transcriptional regulator that acts as a nitric oxide (NO) sensor. Here, the authors present the crystal structure of NsrR, which reveals an unusual Fe-S cluster coordination and explains how NO exposure leads to the degradation of the cluster.

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Bibliografiset tiedot
Päätekijät: Anne Volbeda, Erin L. Dodd, Claudine Darnault, Jason C. Crack, Oriane Renoux, Matthew I. Hutchings, Nick E. Le Brun, Juan C. Fontecilla-Camps
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Portfolio 2017-04-01
Sarja:Nature Communications
Linkit:https://doi.org/10.1038/ncomms15052
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