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Type II Secretion-Dependent Aminopeptidase LapA and Acyltransferase PlaC Are Redundant for Nutrient Acquisition during <italic toggle="yes">Legionella pneumophila</italic> Intracellular Infection of Amoebas

ABSTRACT Legionella pneumophila genes encoding LapA, LapB, and PlaC were identified as the most highly upregulated type II secretion (T2S) genes during infection of Acanthamoeba castellanii, although these genes had been considered dispensable on the basis of the behavior of mutants lacking either l...

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Principais autores: Richard C. White, Felizza F. Gunderson, Jessica Y. Tyson, Katherine H. Richardson, Theo J. Portlock, James A. Garnett, Nicholas P. Cianciotto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018-05-01
coleção:mBio
Assuntos:
Acanthamoeba
acyltransferase
aminopeptidase
Legionella pneumophila
Legionnaires' disease
protease
Acesso em linha:https://journals.asm.org/doi/10.1128/mBio.00528-18
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