Proteomics and metabolomics analyses of camptothecin-producing Aspergillus terreus reveal the integration of PH domain-containing proteins and peptidylprolyl cis/trans isomerase in restoring the camptothecin biosynthesis

ABSTRACT Attenuating the expression of fungal camptothecin biosynthetic genes with subculturing is the challenge that halts their further implementation. The camptothecin productivity of the subcultured Aspergillus terreus has been restored upon addition of Ficus elastica indigenous microbiome; howe...

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Principais autores:	Amgad M. Rady, Ashraf S. A. El-Sayed, Ashraf F. El-Baz, Ghada G. Abdel-Fattah, Sameh Magdeldin, Eman Ahmed, Aya Osama, Sameh E. Hassanein, Hend Saed, Marwa Yassin
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology 2023-12-01
叢編:	Microbiology Spectrum
主題:	camptothecin Aspergillus terreus proteomics analysis metabolomics analysis
在線閱讀:	https://journals.asm.org/doi/10.1128/spectrum.02281-23
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