Histone chaperone HIRA dictate proliferation vs differentiation of chronic myeloid leukemia cells

Abstract Abnormal proliferation and disrupted differentiation of hematopoietic progenitors mark leukemia. Histone cell cycle regulator A (HIRA), a histone chaperone, regulates hemogenic to hematopoietic transition involved in normal hematopoiesis. But, its role remains unexplored in leukemia, a case...

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Главные авторы:	Aditi Majumder, Arya T. Dharan, Ishita Baral, Pallavi Chinnu Varghese, Ananda Mukherjee, Lakshmi Subhadradevi, Geetha Narayanan, Debasree Dutta
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Wiley 2019-09-01
Серии:	FASEB BioAdvances
Предметы:	GATA2 hematopoietic precursors histone variant H3.3 MKL1 proliferation
Online-ссылка:	https://doi.org/10.1096/fba.2019-00014
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