Tumor mutational burden is associated with poor outcomes in diffuse glioma

Abstract Background Tumor mutational burden (TMB) is a potential biomarker for immune checkpoint therapy and prognosis. The impact of TMB on clinical outcomes and the correlation coefficient between exome sequencing and targeted sequencing in glioma have not yet been explored. Methods Somatic mutati...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Lihong Wang, Jia Ge, Yang Lan, Yu Shi, Ying Luo, Yuhuan Tan, Mei Liang, Song Deng, Xia Zhang, Wenying Wang, Yaoyao Tan, Yuanyuan Xu, Tao Luo
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2020-03-01
Σειρά:	BMC Cancer
Θέματα:	TMB Glioma Prognosis Pan-cancer targeted sequencing
Διαθέσιμο Online:	http://link.springer.com/article/10.1186/s12885-020-6658-1
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