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Metabolic Responses of Lung Adenocarcinoma Cells to Survive under Stressful Conditions Associated with Tumor Microenvironment

Solid tumors frequently present a heterogeneous tumor microenvironment. Because tumors have the potential to proliferate quickly, the consequence is a reduction in the nutrients, a reduction in the pH (<6.8), and a hypoxic environment. Although it is often assumed that tumor clones show a similar gr...

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Main Authors: Angeles Carlos-Reyes, Susana Romero-Garcia, Heriberto Prado-Garcia
Format: Artigo
Language:Inglês
Published: MDPI AG 2024-02-01
Series:Metabolites
Subjects:
tumor metabolism
tumor microenvironment
specific growth rate
lactic acidosis
hypoxia
glucose deprivation
Online Access:https://www.mdpi.com/2218-1989/14/2/103
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