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Drug Sensitivity of Vaccine-Derived Rubella Viruses and Quasispecies Evolution in Granulomatous Lesions of Two Ataxia-Telangiectasia Patients Treated with Nitazoxanide

A strong association between rubella virus (RuV) and chronic granulomas, in individuals with inborn errors of immunity, has been recently established. Both the RA27/3 vaccine and wild-type RuV strains were highly sensitive to a broad-spectrum antiviral drug, nitazoxanide (NTZ), in vitro. However, NT...

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Autores principales: Raeesa Faisthalab, Suganthi Suppiah, Morna Dorsey, Kathleen E. Sullivan, Joseph Icenogle, Ludmila Perelygina
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI AG 2022-03-01
Colección:Pathogens
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Acceso en línea:https://www.mdpi.com/2076-0817/11/3/338
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