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CSF metabolites associated with biomarkers of Alzheimer’s disease pathology

IntroductionMetabolomics technology facilitates studying associations between small molecules and disease processes. Correlating metabolites in cerebrospinal fluid (CSF) with Alzheimer’s disease (AD) CSF biomarkers may elucidate additional changes that are associated with early AD pathology and enha...

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Principais autores: Ruocheng Dong, Qiongshi Lu, Hyunseung Kang, Ivonne Suridjan, Gwendlyn Kollmorgen, Norbert Wild, Yuetiva Deming, Carol A. Van Hulle, Rozalyn M. Anderson, Henrik Zetterberg, Kaj Blennow, Cynthia M. Carlsson, Sanjay Asthana, Sterling C. Johnson, Corinne D. Engelman
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-08-01
coleção:Frontiers in Aging Neuroscience
Assuntos:
Alzheimer’s disease
metabolomics
CSF NeuroToolKit biomarkers
metabolome-wide association
Mendelian randomization
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1214932/full
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