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Mapping the chemotactic landscape in NK cells reveals subset-specific synergistic migratory responses to dual chemokine receptor ligationResearch in context

Summary: Background: Natural killer (NK) cells have a unique capability of spontaneous cytotoxicity against malignant cells and hold promise for off-the-shelf cell therapy against cancer. One of the key challenges in the field is to improve NK cell homing to solid tumors. Methods: To gain a deeper...

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Principais autores: Mieszko Lachota, Katarzyna Zielniok, Daniel Palacios, Minoru Kanaya, Leena Peena, Hanna Julie Hoel, Merete Thune Wiiger, Lise Kveberg, Wojciech Hautz, Radosław Zagożdżon, Karl-Johan Malmberg
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2023-10-01
Serier:EBioMedicine
Fag:
NK cells
Natural killer cells
Cancer
Immunology
Migration
Chemokine receptors
Online adgang:http://www.sciencedirect.com/science/article/pii/S2352396423003778
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