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MAIT cells accumulate in placental intervillous space and display a highly cytotoxic phenotype upon bacterial stimulation

Abstract During pregnancy, the maternal immune system must tolerate the developing foetus, and yet retain a potent antimicrobial response to prevent infections. Mucosal associated invariant T (MAIT) cells recognize microbial-derived vitamin B metabolites presented on the MR1 molecule, but their pres...

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Bibliografische gegevens
Hoofdauteurs: Martin Solders, Laia Gorchs, Tom Erkers, Anna-Carin Lundell, Silvia Nava, Sebastian Gidlöf, Eleonor Tiblad, Isabelle Magalhaes, Helen Kaipe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2017-07-01
Reeks:Scientific Reports
Online toegang:https://doi.org/10.1038/s41598-017-06430-6
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