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PRAME promotes epithelial-to-mesenchymal transition in triple negative breast cancer

Abstract Background The triple negative breast cancer (TNBC) paradox marks a major challenge in the treatment-decision making process. TNBC patients generally respond better to neoadjuvant chemotherapy compared to other breast cancer patients; however, they have a substantial higher risk of disease...

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Principais autores: Ghaneya Al-Khadairi, Adviti Naik, Remy Thomas, Boshra Al-Sulaiti, Shaheen Rizly, Julie Decock
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-01-01
coleção:Journal of Translational Medicine
Assuntos:
PRAME
PReferentially Antigen expressed in Melanoma
Triple negative breast cancer
Migration
Invasion
Epithelial-to-mesenchymal transition
Acesso em linha:http://link.springer.com/article/10.1186/s12967-018-1757-3
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