Molecular mechanism of histone variant H2A.B on stability and assembly of nucleosome and chromatin structures

Abstract Background H2A.B, the most divergent histone variant of H2A, can significantly modulate nucleosome and chromatin structures. However, the related structural details and the underlying mechanism remain elusive to date. In this work, we built atomic models of the H2A.B-containing nucleosome c...

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Bibliografische Detailangaben

Hauptverfasser:	Junhui Peng, Chuang Yuan, Xinfan Hua, Zhiyong Zhang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2020-07-01
Schriftenreihe:	Epigenetics & Chromatin
Schlagworte:	Histone variant H2A.B Multiscale modeling Molecular dynamics Coarse-grained simulations
Online-Zugang:	http://link.springer.com/article/10.1186/s13072-020-00351-x
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