A versatile nanobody platform for live and super-resolution imaging of synaptic vesicle dynamics and plasticity in rodent and human neurons

Abstract Synaptic neurotransmission is a critical hallmark of brain activity and one of the first processes affected in neural diseases. Monitoring this process, particularly synaptic vesicle recycling, in living cells has been instrumental in revealing the mechanisms responsible for neurotransmitte...

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Hauptverfasser:	Rashi Goel, Kristina Jevdokimenko, Ronja Rehm, Jannik Hentze, Paola Agüi-Gonzalez, Momchil Ninov, Erik Maier, Yin Wu, Felix Lange, Agata Witkowska, Svenja Bolz, Francesca Pennacchietti, Martina Damenti, Natalie Kaempf, Vladimir Khayenko, Carles Calatayud, Viveka Nand Malviya, Natali L. Chanaday, Emma Scaletti Hutchinson, Hao Liu, Kirsten Weyand, Valentin Schwarze, Daniela Ivanova, Tristan P. Wallis, Christopher Small, Hans M. Maric, Merja Joensuu, Michael A. Cousin, Frédéric A. Meunier, Patrik Verstreken, Ilaria Testa, Ege T. Kavalali, Volker Haucke, Stefan Jakobs, Henning Urlaub, Nils Brose, Benjamin H. Cooper, Pål Stenmark, Felipe Opazo, Reinhard Jahn, Silvio O. Rizzoli, Eugenio F. Fornasiero
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2026-05-01
Schriftenreihe:	Journal of Nanobiotechnology
Schlagworte:	Nanotools Synaptic vesicles Synaptotagmin Presynaptic biology Nanobodies SdAb
Online-Zugang:	https://doi.org/10.1186/s12951-026-04489-w
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