Immunological profiling in type 2 diabetes mellitus and type 2 diabetic kidney disease: insights from single-cell LacNAc sequencing

BackgroundDiabetic kidney disease (DKD), a major complication of type 2 diabetes mellitus (T2DM), is the leading cause of end-stage renal disease (ESRD). Recently, the innate immune system, particularly neutrophils and the process of NET formation, has garnered significant attention for its role in...

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Главные авторы:	Mengyun Xiao, Zigan Xu, Xiaohui Zhu, Jing Chen, Ru Wang, Yaxuan Wang, Xiang Gao, Shaodong Luan, Xiaoyan Pu
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2025-08-01
Серии:	Frontiers in Endocrinology
Предметы:	type 2 diabetes mellitus diabetic kidney disease neutrophil extracellular traps net formation ROS oxidative stress
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fendo.2025.1550925/full
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