Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression
Senescence of mammalian cells is characterized by proliferative arrest and expression of an inflammatory phenotype. Here the authors show the H2A variant H2A.J, found only in mammals, accumulates following persistent DNA damage or natural aging.
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Portfolio
2017-05-01
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| Seria: | Nature Communications |
| Dostęp online: | https://doi.org/10.1038/ncomms14995 |
| Etykiety: |
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