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TGFB2/IGFBP5 activated by transcription factors STAT2 and SMAD3 initiate granulosa cell degeneration and cause follicular atresia in chickens

Follicular atresia is a crucial factor that affects the egg-laying performance of chickens, and granulosa cells (GCs) are the root cause of follicular atresia. Investigating the fate-determining genes of GCs can help improve egg production and laying period duration in chickens. Notably, transformin...

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Principais autores: Wenhui Zhang, Siyu Huang, Axiu Guo, Zongyi Zhao, Bo Zhang, Fuwei Li, Haigang Bao, Hao Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-11-01
coleção:Poultry Science
Assuntos:
Chicken
Follicle atresia
Granulosa cells
SCENIC
Transcription factor
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0032579125009885
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