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Treatment-mediated alterations in HIV fitness preserve CD4+ T cell counts but have minimal effects on viral load.

For most HIV-infected patients, antiretroviral therapy controls viral replication. However, in some patients drug resistance can cause therapy to fail. Nonetheless, continued therapy with a failing regimen can preserve or even lead to increases in CD4+ T cell counts. To understand the biological bas...

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Principais autores: Naveen K Vaidya, Libin Rong, Vincent C Marconi, Daniel R Kuritzkes, Steven G Deeks, Alan S Perelson
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2010-11-01
coleção:PLoS Computational Biology
Acesso em linha:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1001012&type=printable
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