Memory-promoting function of miR-379-5p attenuates CD8+ T cell exhaustion by targeting immune checkpoints

Background MicroRNAs (miRNAs) are epigenetic regulators of T cell maturation and exhaustion. However, the mechanisms by which miRNAs influence T cell function in tumor environments remain unclear. This study focuses on miR-379-5p, which counteracts T cell exhaustion and enhances antitumor responses....

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Chia-Hsin Liu, Hong-Wei Li, Liang-Chih Liu, You-Zhe Lin, Wan-Rong Wu, Ting-Yi Liao, Chuan-Chun Lee, Feng-Chi Chung, Yi-Chun Shen, Guan-Yu Zhuo, Wei-Chung Cheng, Shao-Chun Wang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMJ Publishing Group 2025-04-01
Schriftenreihe:	Journal for ImmunoTherapy of Cancer
Online-Zugang:	https://jitc.bmj.com/content/13/4/e010363.full
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