The polyphenol metabolite urolithin A suppresses myostatin expression and augments glucose uptake in human skeletal muscle cells

Abstract Purpose Polyphenolic plant extracts have demonstrated anti-inflammatory and anti-catabolic effects in vitro, however their meaningful translation into humans remains elusive. Urolithin A (UA), a gut-derived metabolite of ellagitannins, has shown promise for improving muscle function and met...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Andrew Wilhelmsen, Leonidas G Karagounis, Andrew J. Bennett, Davide D’Amico, Andréane M. Fouassier, Simon W. Jones, Kostas Tsintzas
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2025-02-01
Schriftenreihe:	Nutrition & Metabolism
Schlagworte:	Insulin sensitivity Anabolic sensitivity Skeletal muscle Primary human myotubes Urolithin A
Online-Zugang:	https://doi.org/10.1186/s12986-025-00909-0
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!