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PCSK9 inhibitors and inclisiran with or without statin therapy on incident muscle symptoms and creatine kinase: a systematic review and network meta-analysis

BackgroundAtherosclerotic cardiovascular disease (ASCVD), a leading cause of global fatalities, has inconsistent findings regarding the impact of muscle symptoms despite promising clinical trials involving PCSK9 inhibitors (PCSK9i) and siRNA as potential therapeutic options.MethodsThe databases EMBA...

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Hlavní autoři: Wenshu Li, Lichaoyue Sun, Sichao Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2024-07-01
Edice:Frontiers in Cardiovascular Medicine
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fcvm.2024.1375040/full
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