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Induced Pluripotent Stem Cell-Derived Neural Precursors Improve Memory, Synaptic and Pathological Abnormalities in a Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common type of dementia in the elderly population. The disease is characterized by progressive memory loss, cerebral atrophy, extensive neuronal loss, synaptic alterations, brain inflammation, extracellular accumulation of amyloid-β (Aβ) plaques, and intracellula...

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Principais autores: Enrique Armijo, George Edwards, Andrea Flores, Jorge Vera, Mohammad Shahnawaz, Fabio Moda, Cesar Gonzalez, Magdalena Sanhueza, Claudio Soto
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-07-01
Serier:Cells
Fag:
stem cells
therapy
Alzheimer’s disease
amyloid-beta
tau
inflammation
Online adgang:https://www.mdpi.com/2073-4409/10/7/1802
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