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Comparison of DNA methylation measurements from EPIC BeadChip and SeqCap targeted bisulphite sequencing in PON1 and nine additional candidate genes

Epigenome-wide association studies (EWAS) are widely implemented in epidemiology, and the Illumina HumanMethylationEPIC BeadChip (EPIC) DNA microarray is the most-used technology. Recently, next-generation sequencing (NGS)-based methods, which assess DNA methylation at single-base resolution, have b...

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Principais autores: Dennis Khodasevich, Anna R. Smith, Karen Huen, Brenda Eskenazi, Andres Cardenas, Nina Holland
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2022-12-01
Serier:Epigenetics
Fag:
dna methylation
seqcap
ngs-based sequencing
epic microarray
pon1
Online adgang:http://dx.doi.org/10.1080/15592294.2022.2091818
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