Pharmacogenetics in treatment of anthracycline-induced cardiotoxicity in women without prior cardiovascular diseases

Aim. To evaluate the role of polymorphisms in adrenoceptor beta 1 (ADRB1) (Arg389Gly, rs1801253) and angiotensin-converting enzyme (ACE) (I/D, rs4343) genes in assessing the effectiveness of β-blocker (carvedilol) and ACE inhibitor (enalapril) therapy in women with anthracycline-induced cardiotoxici...

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Hlavní autoři:	E. V. Grakova, K. V. Kopeva, S. N. Shilov, E. N. Berezikova, A. A. Popova, M. N. Neupokoeva, E. T. Ratushnyak, V. V. Kalyuzhin, A. T. Teplyakov
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Siberian State Medical University (Tomsk) 2023-01-01
Edice:	Бюллетень сибирской медицины
Témata:	anthracycline-induced cardiotoxicity heart failure gene polymorphisms β-blocker angiotensin-converting enzyme inhibitor
On-line přístup:	https://bulletin.ssmu.ru/jour/article/view/5020
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