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Bone marrow lesion coexisted with subchondral bone attrition and/or subchondral bone cyst is associated with knee pain in knee osteoarthritis regardless of cartilage lesion: the Bunkyo health study

Abstract Background Subchondral bone changes, which include bone marrow lesion (BML), subchondral bone attrition (SBA) and subchondral bone cyst (SBC) by magnetic resonance imaging (MRI) analysis, are reportedly implicated for knee pain in knee osteoarthritis (OA). However, the relationship between...

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Principais autores: Jun Tomura, Haruka Kaneko, Arepati Adili, Takako Aoki, Lizu Liu, Yoshifumi Negishi, Keiichi Yoshida, Keiji Kobayashi, Suguru Wakana, Shinnosuke Hada, Jun Shiozawa, Yuichiro Machiyama, Takuya Yamamura, Takahiro Sasahara, Kengo Sugitani, Mitsuaki Kubota, Yuki Someya, Yoshifumi Tamura, Shuko Nojiri, Takako Negishi-Koga, Yasunori Okada, Muneaki Ishijima
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2025-09-01
coleção:Arthritis Research & Therapy
Assuntos:
Knee osteoarthritis
Knee pain
Subchondral bone changes
Bone marrow lesion
Subchondral bone attrition
Subchondral bone cyst
Acesso em linha:https://doi.org/10.1186/s13075-025-03644-2
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